INT206086

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LDLR) aging (IL6) small molecule metabolic process (LDLR)
lipid metabolic process (LDLR) extracellular space (IL6) extracellular region (IL6)
Anatomy Link Frequency
smooth muscle cells 2
LDLR (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 54 50.00 Quite Low
cytokine 27 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 44 99.60 Very High Very High Very High
Disorder Of Lipid Metabolism 6 75.84 Quite High
Hyperplasia 1 61.48 Quite High
INFLAMMATION 68 50.00 Quite Low
Aging 21 50.00 Quite Low
Osteoporosis 35 5.00 Very Low Very Low Very Low
Diabetes Mellitus 33 5.00 Very Low Very Low Very Low
Cardiovascular Disease 20 5.00 Very Low Very Low Very Low
Disease 19 5.00 Very Low Very Low Very Low
Cancer 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
E-LDL accumulates in human vascular smooth muscle cells (VSMC), where it stimulates the expression of gp130, the signal-transducing chain of the IL-6 receptor (IL-6R) family, and the secretion of Interleukin-6 [83].
E-LDL Positive_regulation (accumulates) of Localization (secretion) of Interleukin-6 in smooth muscle cells
1) Confidence 0.03 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.42 Pain Relevance 0

General Comments

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