INT206089

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FOSB, PTGS2) small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2)
enzyme binding (PTGS2) DNA binding (FOSB) protein complex (PTGS2)
FOSB (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 54 100.00 Very High Very High Very High
metalloproteinase 2 72.56 Quite High
cytokine 27 53.52 Quite High
Inflammatory response 8 40.16 Quite Low
Arthritis 10 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 68 100.00 Very High Very High Very High
Atherosclerosis 44 94.60 High High
Obesity 9 91.64 High High
Adhesions 7 90.56 High High
Apoptosis 8 87.44 High High
Disorder Of Lipid Metabolism 6 83.32 Quite High
Repression 2 82.60 Quite High
Vasculitis 1 58.76 Quite High
Aging 21 50.00 Quite Low
Osteoporosis 35 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Via negative regulation of nuclear factor-kappa B and activator protein-1 signaling pathways, PPAR alpha inhibits expression of inflammatory genes, such as interleukin-6, cyclooxygenase-2, and endothelin-1.
Negative_regulation (regulation) of activator protein-1 Negative_regulation (inhibits) of Gene_expression (expression) of cyclooxygenase-2 associated with inflammation
1) Confidence 0.00 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.97 Pain Relevance 0.19

General Comments

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