INT206133

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.80
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDC42) plasma membrane (CDC42) cytoskeleton (CDC42)
intracellular (CDC42) GTPase activity (CDC42) cell division (CDC42)
CDC42 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 48 68.80 Quite High
cytokine 31 59.48 Quite High
Inflammation 67 58.52 Quite High
metalloproteinase 2 47.64 Quite Low
Kinase C 18 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
Antihistamine 10 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 6 99.26 Very High Very High Very High
Rhinitis 127 98.76 Very High Very High Very High
Cancer 146 66.72 Quite High
Aging 31 59.48 Quite High
INFLAMMATION 85 58.52 Quite High
Adhesions 7 55.00 Quite High
Atherosclerosis 44 51.76 Quite High
Apoptosis 11 39.88 Quite Low
Chronic Sinusitis 1 36.64 Quite Low
Disease 32 28.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have established Raichu-FLIM [37], whereby upon GTP binding, Rac1/Cdc42/RhoA exhibits a higher affinity towards the corresponding RhoGTPase-interacting domain, bringing the two different fluorescent proteins of the biosensor into close proximity and enabling FRET between GFP and mRFP1.
Cdc42 Binding (binding) of
1) Confidence 0.25 Published 2009 Journal Target Oncol Section Body Doc Link PMC2778706 Disease Relevance 0.13 Pain Relevance 0.06
1) ARIA: Allergic Rhinitis and its Impact on Asthma; 2) RSDI: rhinosinusitis disability index; 3) cdc42: cell division cycle 42; 4) TRP: transient receptor potential; 5) ACE: angiotensin converting enzyme; 6) CT: computed tomography; 7) HEPA: high-efficiency particulate air; 8) BCG-PSN: polysaccharide nucleic acid fraction of the Bacillus Calmette-Guérin vaccine; 9) FDA: Food and Drug Administration

Competing interests

cdc42 Binding (index) of associated with asthma and rhinitis
2) Confidence 0.17 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2885381 Disease Relevance 0.50 Pain Relevance 0
The Rho branch constitutes a second major branch, with RhoA, Rac1 and Cdc42 the most studied members.
Cdc42 Binding (branch) of
3) Confidence 0.06 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.17 Pain Relevance 0.06

General Comments

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