INT20616

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Context Info
Confidence 0.68
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.61
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (F2) peptidase activity (F2) extracellular space (F2)
extracellular region (F2) response to stress (F2)
Anatomy Link Frequency
plasma 1
blood 1
platelets 1
F2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
abdominal pain 1 90.72 High High
depression 1 67.92 Quite High
Pain 4 62.72 Quite High
Inflammation 23 50.00 Quite Low
Analgesic 14 50.00 Quite Low
Paracetamol 5 50.00 Quite Low
transdermal 3 11.92 Low Low
cINOD 15 5.00 Very Low Very Low Very Low
anesthesia 9 5.00 Very Low Very Low Very Low
Pain threshold 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Abscess 3 97.96 Very High Very High Very High
Hemorrhage 23 94.56 High High
Amebiasis 1 94.20 High High
Hepatomegaly 1 93.28 High High
Fever 1 92.16 High High
Anaemia 2 91.60 High High
Abdominal Pain 1 90.72 High High
Liver Abscess 2 85.20 High High
Poisoning 4 81.16 Quite High
Amebic Liver Abscess 1 80.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aureus). 80 to 90% of patients presented abnormal prothrombin time.
Localization (presented) of prothrombin
1) Confidence 0.68 Published 1990 Journal G E N Section Abstract Doc Link 2152311 Disease Relevance 0.89 Pain Relevance 0.09
Does point of care prothrombin time measurement reduce the transfusion of fresh frozen plasma in patients undergoing major surgery?
Localization (measurement) of prothrombin in plasma
2) Confidence 0.57 Published 2009 Journal Trials Section Title Doc Link PMC2785779 Disease Relevance 0.32 Pain Relevance 0
The release from the reference was higher than that from formulation F2.
Localization (release) of F2
3) Confidence 0.42 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2990385 Disease Relevance 0 Pain Relevance 0
The effects of age, nature (single or multiple) and stated size of overdose, hepatic enzyme induction (gamma-glutamyl transpeptidase, GGT), degree of liver injury (aspartate aminotransferase, prothrombin time), blood pressure and renal injury were assessed.
Localization (degree) of prothrombin in blood
4) Confidence 0.05 Published 2009 Journal Eur. J. Clin. Pharmacol. Section Body Doc Link 18958458 Disease Relevance 0.08 Pain Relevance 0
Platelet activation markers for ex vivo analysis may include a) activation-dependent epitopes of the membrane glycoprotein (GP) IIb/IIIa (CD41a) receptor, as demonstrated by the binding of activation-specific monoclonal antibodies (MoAbs) PAC1, anti-LIBS1 and anti-RIBS); b) the expression of P-selectin (CD62p), the alpha-granule GP translocated to the platelet surface following release reaction; and c) platelet procoagulant activity, as demonstrated by the binding of i) annexin V protein to the prothrombinase-complex (prothrombin, activated factor X (Xa) and V (Va)) binding sites on the surface of activated platelets, and of ii) MoAbs against activated coagulation factors V and X bound to the surface of activated platelets.
Localization (translocated) of prothrombin in platelets
5) Confidence 0.04 Published 2004 Journal J. Biol. Regul. Homeost. Agents Section Abstract Doc Link 15471223 Disease Relevance 0.31 Pain Relevance 0.10

General Comments

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