INT206251

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Context Info
Confidence 0.66
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD24) signal transducer activity (CD24)
Anatomy Link Frequency
T cells 1
CD24 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 190 73.44 Quite High
Central nervous system 10 45.72 Quite Low
Angina 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 50 88.00 High High
Multiple Sclerosis 202 73.44 Quite High
Systemic Lupus Erythematosus 98 72.00 Quite High
Disease 16 5.00 Very Low Very Low Very Low
Disease Progression 6 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 4 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Interstitial Lung Diseases 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For the mRNA stability data, an analysis of variance was performed to test the hypothesis that P1527 modulates CD24 mRNA stability.
Protein_catabolism (stability) of CD24
1) Confidence 0.66 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 0 Pain Relevance 0
Since CD24 was expressed at high levels among some lineages of hematopoietic cells and in the transfected CHO cells, the reduction in the steady levels may underestimate the reduction in other cell types, such as T cells, in which CD24 is expressed at lower levels and is therefore less likely to saturate the degradation system.
Protein_catabolism (degradation) of CD24 in T cells
2) Confidence 0.66 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1847692 Disease Relevance 0.62 Pain Relevance 0.11

General Comments

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