INT20626

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Context Info
Confidence 0.35
First Reported 1990
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.80
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CHKB)
Anatomy Link Frequency
muscle 4
CHKB (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 47 99.36 Very High Very High Very High
tetrodotoxin 2 64.40 Quite High
agonist 4 12.04 Low Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Paralysis 10 92.28 High High
Targeted Disruption 2 35.20 Quite Low
Cancer 16 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Cervical Cancer 1 5.00 Very Low Very Low Very Low
Genetic Translocation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our studies demonstrate that in human muscle: (1) total enzymatic activities and the expression of MSIs of GP and PGAM are regulated by neuronal effect(s); (2) total enzymatic activities of CK, LDH, and AChE depend mainly on muscle contractile activity; and (3) MSIs of CK and LDH are regulated predominantly by neuronal factors and to a much lesser degree by muscle contractile activity.
Regulation (regulated) of Gene_expression (expression) of CK in muscle
1) Confidence 0.35 Published 1990 Journal J. Neurochem. Section Abstract Doc Link 2152794 Disease Relevance 0.40 Pain Relevance 0.06
Our studies demonstrate that in human muscle: (1) total enzymatic activities and the expression of MSIs of GP and PGAM are regulated by neuronal effect(s); (2) total enzymatic activities of CK, LDH, and AChE depend mainly on muscle contractile activity; and (3) MSIs of CK and LDH are regulated predominantly by neuronal factors and to a much lesser degree by muscle contractile activity.
Regulation (regulated) of Gene_expression (expression) of CK in muscle
2) Confidence 0.35 Published 1990 Journal J. Neurochem. Section Abstract Doc Link 2152794 Disease Relevance 0.40 Pain Relevance 0.06
Hence, PKC was implicated in the Receptor Ck signaling pathway controlling the transcription of c-myc, PPAR?
Regulation (signaling) of Gene_expression (pathway) of Ck associated with kinase c
3) Confidence 0.25 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0 Pain Relevance 0.41

General Comments

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