INT206428

Context Info Confidence 0.28 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0.03

cytoplasm (SULT1B1, ASAP1) cytosol (SULT1B1) signal transduction (ASAP1) small molecule metabolic process (SULT1B1)

SULT1B1 (Homo sapiens) ASAP1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 1 67.80 adenocard 2 42.04 Catecholamine 9 20.88 Dopamine 8 5.00 Neurotransmitter 2 5.00 Paracetamol 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 1 67.80 Cancer 1 66.92

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These five include known inhibitors (quercetin, DBHD, PLP, and PCP), as well as isoprenaline, which binds to SULT1B1 only in the absence of PAP and is a poor substrate for this enzyme (Tables 1 and 2).

SULT1B1 Binding (binds) of PAP

1) Confidence 0.28 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1847840 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

This test has worked.