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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.28
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASAP1) cytoplasm (ASAP1)
Anatomy Link Frequency
mitral valve 2
ASAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 2 70.24 Quite High
agonist 1 62.72 Quite High
cva 10 34.04 Quite Low
Kinase C 14 9.24 Low Low
Inflammation 16 5.00 Very Low Very Low Very Low
Catecholamine 9 5.00 Very Low Very Low Very Low
Dopamine 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Alveolar Proteinosis 34 100.00 Very High Very High Very High
Congenital Anomalies 5 92.96 High High
Hemorrhage 3 92.84 High High
Increased Venous Pressure Under Development 11 90.88 High High
Cv General 2 Under Development 1 90.48 High High
Pressure Volume 2 Under Development 4 90.28 High High
Pulmonary Hypertension 82 88.08 High High
Respiratory Failure 4 87.04 High High
INFLAMMATION 19 69.92 Quite High
Failure To Thrive 3 55.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to rule out the possibility that SULT4A1 simply has a much weaker affinity for PAP, we performed titration experiments for several of the proteins with increasing concentrations of PAP ranging from 90 ?
Positive_regulation (increasing) of Positive_regulation (concentrations) of PAP
1) Confidence 0.41 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1847840 Disease Relevance 0 Pain Relevance 0
In a third, patientsÂ’ status post mitral valve surgery or left ventricular assist device (LVAD) placement who received sildenafil for elevated PAP had significant improvement in MAP, mPAP, and PVRI.
Positive_regulation (improvement) of Positive_regulation (elevated) of PAP in mitral valve
2) Confidence 0.15 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 0.40 Pain Relevance 0.03
The infusion of rhAPC, however, decreased the LPS-induced elevations of PAP, Pmo and PVRIdwn with intergroup differences (P < 0.05).
Positive_regulation (induced) of Positive_regulation (elevations) of PAP
3) Confidence 0.14 Published 2008 Journal Crit Care Section Body Doc Link PMC2575593 Disease Relevance 0.34 Pain Relevance 0.04
These are the first results to demonstrate familial primary PAP in humans and that GM-CSF-R?
Positive_regulation (familial) of Positive_regulation (primary) of PAP associated with pulmonary alveolar proteinosis
4) Confidence 0.12 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2585845 Disease Relevance 0.54 Pain Relevance 0

General Comments

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