INT206513

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 8.32
Pain Relevance 3.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 1
immune system 1
T-cell 1
Eae1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 50 99.98 Very High Very High Very High
Inflammation 148 99.80 Very High Very High Very High
cytokine 70 99.28 Very High Very High Very High
Multiple sclerosis 86 98.52 Very High Very High Very High
b2 receptor 34 95.08 Very High Very High Very High
agonist 44 95.00 High High
Central nervous system 176 94.96 High High
metalloproteinase 102 94.72 High High
Inflammatory response 13 90.84 High High
Inflammatory stimuli 2 86.20 High High
Disease Link Frequency Relevance Heat
Multiple Sclerosis 382 100.00 Very High Very High Very High
Disease 133 100.00 Very High Very High Very High
Hypersensitivity 79 100.00 Very High Very High Very High
INFLAMMATION 166 99.80 Very High Very High Very High
Sprains And Strains 4 98.80 Very High Very High Very High
Targeted Disruption 31 95.44 Very High Very High Very High
Demyelinating Disease 46 94.36 High High
Adhesions 28 88.08 High High
Neurodegenerative Disease 2 79.60 Quite High
Central Nervous System Disease 6 79.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The MOG peptide can induce typical EAE disease in C57BL/6 mice and in other strains.
Localization (disease) of EAE associated with multiple sclerosis, sprains and strains and disease
1) Confidence 0.26 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2596102 Disease Relevance 1.92 Pain Relevance 0.74
In order to assess the involvement of kinin receptors in the cerebral chemokine release after EAE induction, brain tissues from WT and B2-/- were examined.
Localization (release) of EAE in brain associated with chemokine and multiple sclerosis
2) Confidence 0.24 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2596102 Disease Relevance 1.11 Pain Relevance 0.27
Microglial expression of MMP-14 and 16 (Fig. 2A and 2C) were not significantly altered in EAE.
Neg (not) Localization (altered) of EAE associated with multiple sclerosis
3) Confidence 0.11 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2075488 Disease Relevance 0.86 Pain Relevance 0.23
In EAE, auto-reactive CD4+ TH1 cells secrete pro-inflammatory cytokines such as IFN?
Localization (secrete) of EAE associated with multiple sclerosis, inflammation and cytokine
4) Confidence 0.09 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1851623 Disease Relevance 1.37 Pain Relevance 0.59
EAE in association with inhibition of T-cell proliferation and secretion of
Localization (secretion) of EAE in T-cell associated with multiple sclerosis
5) Confidence 0.05 Published 2008 Journal PPAR Research Section Body Doc Link PMC2490815 Disease Relevance 2.03 Pain Relevance 0.97
Effects of PEG minocycline-liposomes on the clinical course of EAE
Localization (course) of EAE associated with multiple sclerosis
6) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2613526 Disease Relevance 0.55 Pain Relevance 0.18
After multiple injections, physiological aspects of the immune system become altered and allergy-related IgE antibody levels are brought into balance with immune mediators that do not induce allergic responses and related histamine release (for a concise review, see: [29]).
Localization (release) of allergic in immune system associated with hypersensitivity
7) Confidence 0.01 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2949815 Disease Relevance 0.46 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox