INT206524

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.66
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sema5b)
Anatomy Link Frequency
tail 1
Sema5b (Mus musculus)
Pain Link Frequency Relevance Heat
tail-flick 2 97.96 Very High Very High Very High
Thermal hyperalgesia 11 91.40 High High
Inflammation 62 89.28 High High
withdrawal 13 84.68 Quite High
cytokine 20 84.24 Quite High
Central nervous system 36 80.88 Quite High
dorsal root ganglion 24 59.92 Quite High
Inflammatory mediators 1 58.72 Quite High
Hyperalgesia 15 50.00 Quite Low
allodynia 9 43.00 Quite Low
Disease Link Frequency Relevance Heat
Apoptosis 26 92.60 High High
Hyperalgesia 34 91.40 High High
INFLAMMATION 63 89.28 High High
Multiple Sclerosis 88 60.88 Quite High
Ganglion Cysts 46 59.92 Quite High
Neuropathic Pain 28 43.00 Quite Low
Disease 23 36.16 Quite Low
Pain 26 5.00 Very Low Very Low Very Low
Demyelinating Disease 11 5.00 Very Low Very Low Very Low
Non-diabetic Peripheral Neuropathy 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In detail, TREM2-transduced BM-MC released 130 pg/ml IL-10 (SEM 52) after stimulation with LPS- and TREM2-specific antibodies (Figure 3D).


Localization (released) of SEM
1) Confidence 0.10 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1851623 Disease Relevance 0.44 Pain Relevance 0.31
Latency to vigorous tail flick was recorded during three trials separated by at least 30 min and the three trials were averaged and presented as mean ± SEM.
Localization (presented) of SEM in tail associated with tail-flick
2) Confidence 0.07 Published 2010 Journal Mol Pain Section Body Doc Link PMC2848188 Disease Relevance 0.22 Pain Relevance 0.34

General Comments

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