INT206605

Context Info Confidence 0.11 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.41 Pain Relevance 0.32

cell adhesion (Itgb5)

Anatomy Link Frequency ECM 1 Itgb5 (Mus musculus)

Pain Link Frequency Relevance Heat Morphine 49 87.84 cocaine 9 77.76 withdrawal 2 62.32 addiction 1 43.56 nMDA receptor 1 29.04 long-term potentiation 6 27.32 depression 5 10.64 Catechol-O-methyltransferase 46 5.00 Nucleus accumbens 24 5.00 Dopamine 11 5.00

Disease Link Frequency Relevance Heat Sprains And Strains 83 94.84 Adhesions 2 93.48 Drug Dependence 3 43.56 Depression 5 10.64 Urological Neuroanatomy 10 5.00 Pain 2 5.00 Dislocations 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Several extracellular matrix (ECM) genes (collagen and laminins) were identified, as were two integrins (beta5 and alpha2), which can bind to ECM proteins.

beta5 Binding (bind) of in ECM

1) Confidence 0.11 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1851712 Disease Relevance 0.41 Pain Relevance 0.32

General Comments

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