INT206664

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Context Info
Confidence 0.20
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.59
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CISH) intracellular (CISH) molecular_function (CISH)
cellular_component (CISH)
CISH (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 17 100.00 Very High Very High Very High
Pain 17 93.12 High High
depression 10 85.56 High High
intrathecal 14 83.16 Quite High
Inflammation 37 80.72 Quite High
imagery 23 76.12 Quite High
metalloproteinase 27 75.44 Quite High
Central nervous system 13 61.48 Quite High
Multiple sclerosis 40 35.16 Quite Low
Catecholamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 17 93.12 High High
Post-partum Depression 4 85.56 High High
INFLAMMATION 36 80.72 Quite High
Central Nervous System Disease 13 61.48 Quite High
Recurrence 5 59.36 Quite High
Disease 21 54.76 Quite High
Encephalitis 6 50.00 Quite Low
Demyelinating Disease 45 35.16 Quite Low
Neurological Disease 16 5.00 Very Low Very Low Very Low
Fatigue 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CIS Checklist Individual Strength

Competing interests

Positive_regulation (interests) of Gene_expression (interests) of CIS
1) Confidence 0.20 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1851952 Disease Relevance 0.27 Pain Relevance 0.23
Further, CSF and serum CxCL-13 levels of patients with CIS, RRMS and CPMS had similar ranges and also CSF?
Positive_regulation (serum) of Gene_expression (levels) of CIS
2) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2438478 Disease Relevance 0.32 Pain Relevance 0.35
By comparison of the traces for CAT (a, c) and CHR (b,d) there was no evidence for Mn2+ entry in response to either peptide, consistent with activation of SOCs selective for Ca2+ and non-permeable for Mn2+ in PMNs [38].


Positive_regulation (activation) of Gene_expression (selective) of SOCs associated with calcium channel
3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0 Pain Relevance 0.16

General Comments

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