INT206766

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nkx1-1) neurological system process (Nkx1-1)
Anatomy Link Frequency
synapses 3
Ltp (Mus musculus)
Nkx1-1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
long-term potentiation 97 100.00 Very High Very High Very High
c fibre 42 100.00 Very High Very High Very High
Spinal cord 18 99.24 Very High Very High Very High
Glutamate receptor 2 98.16 Very High Very High Very High
Calcium channel 1 94.96 High High
substance P 6 78.32 Quite High
agonist 4 76.84 Quite High
Sciatic nerve 8 73.96 Quite High
nMDA receptor 2 72.72 Quite High
depression 6 71.32 Quite High
Disease Link Frequency Relevance Heat
Anaerobic Bacterial Infections 1 78.12 Quite High
Depression 6 71.32 Quite High
Pain 40 50.00 Quite Low
Nociception 15 21.92 Low Low
Hyperalgesia 15 5.00 Very Low Very Low Very Low
Li-fraumeni Syndrome 10 5.00 Very Low Very Low Very Low
Neuropathic Pain 7 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Induction of LTP at C-fibre-synapses requires co-activation of NK1 and NK2 receptors [9], opening of ionotropic glutamate receptors of the NMDA type [8,12,13], opening of T-type voltage-gated calcium channels [8,12], and activation of group I but not group II or III metabotropic glutamate receptors [31].
Positive_regulation (Induction) of LTP in synapses Positive_regulation (requires) of Positive_regulation (activation) of NK1 in synapses associated with c fibre, calcium channel, glutamate receptor and long-term potentiation
1) Confidence 0.01 Published 2007 Journal Mol Pain Section Body Doc Link PMC1852298 Disease Relevance 0.22 Pain Relevance 1.16

General Comments

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