INT206844

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ESR1, ANXA1) protein complex (ESR1, ANXA1) cytoplasm (ESR1, ANXA1)
signal transduction (ESR1, ANXA1) nucleoplasm (ESR1) DNA binding (ESR1)
Anatomy Link Frequency
CCRF-CEM 2
ESR1 (Homo sapiens)
ANXA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukemia 1 97.88 Very High Very High Very High
Uterine Fibroids 72 29.92 Quite Low
Cancer 22 7.36 Low Low
Rheumatoid Arthritis 23 5.00 Very Low Very Low Very Low
Apoptosis 9 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Endometriosis (extended) 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Castro-Caldas et al [33] demonstrated that estrogen induced de novo expression of annexin A1 (ANXA1) and stimulated its secretion in the human CCRF-CEM acute lymphoblastic leukemia cell line apparently via a mechanism independent of the intracellular estrogen receptor.
estrogen Positive_regulation (induced) of Gene_expression (expression) of ANXA1 in CCRF-CEM associated with leukemia
1) Confidence 0.08 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 0.10 Pain Relevance 0

General Comments

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