INT206853

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.39
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ESR1, PCP4) nucleoplasm (ESR1) enzyme binding (ESR1)
DNA binding (ESR1) protein complex (ESR1) cytoplasm (ESR1)
ESR1 (Homo sapiens)
PCP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
calcitonin gene related peptide 2 82.00 Quite High
Central nervous system 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 44 100.00 Very High Very High Very High
Apoptosis 18 100.00 Very High Very High Very High
Uterine Fibroids 144 99.08 Very High Very High Very High
Rheumatoid Arthritis 46 59.60 Quite High
Smooth Muscle Tumor 2 46.60 Quite Low
Disease 10 5.00 Very Low Very Low Very Low
Neuroblastoma 6 5.00 Very Low Very Low Very Low
Endometriosis (extended) 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, estrogen may promote cell survival and tumor growth by increasing expression of the anti-apoptotic PCP4 gene and by suppressing the expression of growth inhibitory receptors PTGER3 and TGF-?
estrogen Positive_regulation (increasing) of Gene_expression (expression) of PCP4 associated with cancer and apoptosis
1) Confidence 0.08 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 0.85 Pain Relevance 0.04
Firstly, estrogen increased expression of the anti-apoptotic PCP4 gene and suppressed the expression of growth inhibitory receptors PTGER3 and TGFBR2.
estrogen Positive_regulation (increased) of Gene_expression (expression) of PCP4 associated with apoptosis
2) Confidence 0.07 Published 2007 Journal BMC Womens Health Section Abstract Doc Link PMC1852551 Disease Relevance 0.54 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox