INT206862

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.76
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (ANXA1) cilium (ANXA1) protein complex (ANXA1)
lipid metabolic process (ANXA1) cytoplasm (ANXA1) signal transduction (ANXA1)
Anatomy Link Frequency
uterus 2
ANXA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 1 82.36 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 60 97.88 Very High Very High Very High
Breast Cancer 56 97.36 Very High Very High Very High
Uterine Fibroids 72 92.88 High High
Carcinoma 6 85.60 High High
Chromosome Aberrations 1 85.36 High High
Metastasis 2 84.64 Quite High
Apoptosis 9 76.64 Quite High
Rheumatoid Arthritis 23 73.28 Quite High
Disease 5 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
WalBC cells showed regulated expression of DSP, s100A14 and ANXA1 which are genes associated with well-differentiated, epithelioid breast cancer cell lines with weak invasive potential and poorly invasive tumors [45-47].
Regulation (regulated) of Gene_expression (expression) of ANXA1 associated with cancer and breast cancer
1) Confidence 0.18 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2263075 Disease Relevance 0.92 Pain Relevance 0
It is worthwhile to note that directions of expression changes of ANXA1, NR4A1 and PLP1 were opposite from that of the estrogen treated rat uterus.
Regulation (changes) of Gene_expression (expression) of ANXA1 in uterus
2) Confidence 0.13 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 0.83 Pain Relevance 0.04

General Comments

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