INT206863

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.88
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PCP4) nucleus (PCP4)
Anatomy Link Frequency
uterine 1
PCP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
calcitonin gene related peptide 3 82.00 Quite High
Central nervous system 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 27 100.00 Very High Very High Very High
Cancer 66 99.56 Very High Very High Very High
Uterine Fibroids 216 99.12 Very High Very High Very High
Disease 15 91.08 High High
Rheumatoid Arthritis 69 80.40 Quite High
Neuroblastoma 9 72.28 Quite High
Hyperplasia 3 47.96 Quite Low
Obesity 3 46.76 Quite Low
Smooth Muscle Tumor 3 45.84 Quite Low
Chromosome Aberrations 3 5.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Firstly, estrogen increased expression of the anti-apoptotic PCP4 gene and suppressed the expression of growth inhibitory receptors PTGER3 and TGFBR2.
Gene_expression (expression) of PCP4 associated with apoptosis
1) Confidence 0.28 Published 2007 Journal BMC Womens Health Section Abstract Doc Link PMC1852551 Disease Relevance 0.54 Pain Relevance 0
Functional and pathway analyses suggested multiple molecular mechanisms for estrogen-dependent growth of human uterine fibroids: enhanced tumor cell survival by increased expression of PCP4 and decreased expression of TGF-?
Gene_expression (expression) of PCP4 in uterine associated with uterine fibroids and cancer
2) Confidence 0.28 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 1.56 Pain Relevance 0
Thus, estrogen may promote cell survival and tumor growth by increasing expression of the anti-apoptotic PCP4 gene and by suppressing the expression of growth inhibitory receptors PTGER3 and TGF-?
Gene_expression (expression) of PCP4 associated with cancer and apoptosis
3) Confidence 0.28 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 0.78 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox