INT206869

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Context Info
Confidence 0.38
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 2.51
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ALDH1A2) oxidoreductase activity (ALDH1A2) nucleus (ALDH1A2)
cytoplasm (ALDH1A2)
Anatomy Link Frequency
retina 3
uterine 1
ALDH1A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 3 86.08 High High
alcohol 1 67.32 Quite High
fibrosis 1 30.32 Quite Low
Central nervous system 1 8.72 Low Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 23 99.50 Very High Very High Very High
Endometroid Carcinoma 21 95.88 Very High Very High Very High
Uterine Fibroids 77 93.80 High High
Carcinoma 61 91.08 High High
Endometrial Cancer 153 86.48 High High
Cancer 110 85.92 High High
Skin Cancer 1 69.52 Quite High
Aggression 3 64.64 Quite High
Microsatellite Instability 47 61.12 Quite High
Microphthalmia 3 51.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Westin and colleague [14] described that expression of estrogen-induced genes, RALDH2, EIG121, SFRP1, SFRP4, IGF-1, and IGF-IR, tend to be highest in the well-to-moderately differentiated endometrioid carcinoma.
Gene_expression (expression) of RALDH2 associated with endometroid carcinoma
1) Confidence 0.38 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 0.98 Pain Relevance 0
Previous studies in rodents have suggested that estrogen directly induces uterine RA synthesis by increasing expression of epithelial retinal dehydrogenase (eRolDH) and ALDH1A2 (reviewed in [29]).
Gene_expression (expression) of ALDH1A2 in uterine associated with rheumatoid arthritis
2) Confidence 0.35 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 1.32 Pain Relevance 0.03
which promotes protein translation from tRNAi and mRNA, macrophage capping protein which is an actin-regulatory protein, aldehyde dehydrogenase 1 A2 isoform 1 (ALDH1A2) that catalyzes the synthesis of retinoic acid in the retina, tubulin ?
Gene_expression (aldehyde) of ALDH1A2 in retina
3) Confidence 0.20 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2994335 Disease Relevance 0.05 Pain Relevance 0.04
which promotes protein translation from tRNAi and mRNA, macrophage capping protein which is an actin-regulatory protein, aldehyde dehydrogenase 1 A2 isoform 1 (ALDH1A2) that catalyzes the synthesis of retinoic acid in the retina, tubulin ?
Gene_expression (aldehyde) of dehydrogenase 1 A2 isoform 1 in retina
4) Confidence 0.17 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2994335 Disease Relevance 0.05 Pain Relevance 0.04
which promotes protein translation from tRNAi and mRNA, macrophage capping protein which is an actin-regulatory protein, aldehyde dehydrogenase 1 A2 isoform 1 (ALDH1A2) that catalyzes the synthesis of retinoic acid in the retina, tubulin ?
Gene_expression (macrophage) of dehydrogenase 1 A2 isoform 1 in retina
5) Confidence 0.17 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2994335 Disease Relevance 0.11 Pain Relevance 0.04

General Comments

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