INT206884

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.57
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CRABP2) signal transduction (CRABP2) nucleolus (CRABP2)
nucleus (CRABP2) cytoplasm (CRABP2)
Anatomy Link Frequency
uterine 1
CRABP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 2 78.76 Quite High
fibrosis 2 41.76 Quite Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 46 99.80 Very High Very High Very High
Adenocarcinoma 62 99.32 Very High Very High Very High
Squamous Cell Carcinoma 61 99.04 Very High Very High Very High
Uterine Fibroids 144 97.12 Very High Very High Very High
Cancer 84 96.52 Very High Very High Very High
Apoptosis 18 77.80 Quite High
Death 3 50.76 Quite High
Colon Cancer 2 45.72 Quite Low
Cirrhosis 2 41.76 Quite Low
Lung Cancer 56 41.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our integrated analysis of expression data collected by independent studies revealed that expression of two genes, ALDH1A1 and CRABP2 for RA synthesis or mobilization was differentially expressed in human uterine fibroids and regulated by estrogen in the rat uterus.
Gene_expression (expression) of CRABP2 in uterine associated with uterine fibroids and rheumatoid arthritis
1) Confidence 0.40 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 1.46 Pain Relevance 0.04
Five out of the 17 genes (CRABP2, CRIP2, FOS, JAG1, and MST1R) were among the differentially expressed markers between AD and SCC in the original report publishing the Database 1 [16].
Gene_expression (expressed) of CRABP2 associated with squamous cell carcinoma and adenocarcinoma
2) Confidence 0.36 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2633354 Disease Relevance 1.38 Pain Relevance 0
Lastly, estrogen affects retinoic acid (RA) synthesis and mobilization by regulating expression of CRABP2 and ALDH1A1.
Gene_expression (expression) of CRABP2 associated with rheumatoid arthritis
3) Confidence 0.31 Published 2007 Journal BMC Womens Health Section Abstract Doc Link PMC1852551 Disease Relevance 0.73 Pain Relevance 0

General Comments

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