INT206929

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 6.14
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (XRCC1) nucleus (XRCC1) intracellular (XRCC1)
Anatomy Link Frequency
skin 4
XRCC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 4 83.08 Quite High
Paracetamol 3 82.24 Quite High
aspirin 1 78.56 Quite High
abdominal pain 2 68.96 Quite High
Central nervous system 2 65.68 Quite High
backache 2 62.16 Quite High
Angina 2 45.92 Quite Low
Crohn's disease 2 38.24 Quite Low
imagery 6 8.44 Low Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 125 100.00 Very High Very High Very High
Renal Cancer 106 100.00 Very High Very High Very High
Fever 2 100.00 Very High Very High Very High
Jaundice 2 100.00 Very High Very High Very High
Hematuria 10 99.68 Very High Very High Very High
Endometriosis (extended) 1 95.40 Very High Very High Very High
Disease 29 93.92 High High
Cancer 148 90.72 High High
Syndrome 4 88.96 High High
Infarction 2 74.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most

of the cases of RCC are sporadic; however there are some defined types of RCC

Negative_regulation (defined) of Gene_expression (types) of RCC associated with renal cancer
1) Confidence 0.25 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581742 Disease Relevance 1.45 Pain Relevance 0.49
Our study also found that As exposure has a profound negative impact on DNA repair, decreasing positive expression for XRCC1, MGMT, and hMSH2 mRNA with the increasing severity of skin lesion in arsenicosis patients (Table 3).
Negative_regulation (positive) of Gene_expression (expression) of XRCC1 in skin
2) Confidence 0.21 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1852665 Disease Relevance 0.12 Pain Relevance 0
Our study also found that As exposure has a profound negative impact on DNA repair, decreasing positive expression for XRCC1, MGMT, and hMSH2 mRNA with the increasing severity of skin lesion in arsenicosis patients (Table 3).
Negative_regulation (decreasing) of Gene_expression (expression) of XRCC1 in skin
3) Confidence 0.21 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1852665 Disease Relevance 0.12 Pain Relevance 0
Prognostic of those RCC diagnosed
Negative_regulation (diagnosed) of Gene_expression (Prognostic) of RCC associated with carcinoma
4) Confidence 0.14 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2629071 Disease Relevance 2.25 Pain Relevance 0.13
manifestations of RCC such as fever or jaundice are extremely rare in front of
Negative_regulation (rare) of Gene_expression (manifestations) of RCC associated with carcinoma, jaundice and fever
5) Confidence 0.14 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2629071 Disease Relevance 2.18 Pain Relevance 0.11

General Comments

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