INT206957

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.01
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lipg) extracellular space (Lipg) extracellular region (Lipg)
lipid metabolic process (Lipg)
Anatomy Link Frequency
muscles 6
EDL 2
Lipg (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 58.32 Quite High
ischemia 3 42.84 Quite Low
Arthritis 12 5.00 Very Low Very Low Very Low
anesthesia 10 5.00 Very Low Very Low Very Low
Inflammatory mediators 7 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 19 95.84 Very High Very High Very High
Increased Venous Pressure Under Development 11 83.36 Quite High
Rupture 3 80.84 Quite High
Fatigue 51 74.16 Quite High
Arthritis 28 67.68 Quite High
Urological Neuroanatomy 8 60.28 Quite High
INFLAMMATION 40 58.32 Quite High
Pressure And Volume Under Development 6 52.64 Quite High
Granuloma 1 52.08 Quite High
Cv Unclassified Under Development 3 42.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Widespread micro-dystrophin expression was observed in the TA and EDL muscles of mice receiving rAAV6 and rAAV8 at all three time points (Fig. 1B).
Negative_regulation (observed) of Gene_expression (muscles) of EDL in muscles
1) Confidence 0.08 Published 2007 Journal J Transl Med Section Body Doc Link PMC2082019 Disease Relevance 0.23 Pain Relevance 0
Both MeDL and rofecoxib produced a dose-dependent
Negative_regulation (dose) of Gene_expression (produced) of MeDL
2) Confidence 0.06 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC1852887 Disease Relevance 0.64 Pain Relevance 0.03
The loss of contractile function that was observed after exposure to oxypurinol in electrically stimulated EDL and soleus muscles or PEG-SOD in EDL muscles suggests that these agents alter processes within the intact muscle cell.
Negative_regulation (loss) of Gene_expression (muscles) of EDL in muscles
3) Confidence 0.05 Published 2010 Journal American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Section Body Doc Link PMC2806206 Disease Relevance 0.07 Pain Relevance 0
The data in Table 1 show that prevention of superoxide generation by inhibition of XO activity depressed skeletal muscle force production in EDL and soleus muscles.
Negative_regulation (depressed) of Gene_expression (production) of EDL in muscles
4) Confidence 0.05 Published 2010 Journal American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Section Body Doc Link PMC2806206 Disease Relevance 0.06 Pain Relevance 0
Oxypurinol decreased the maximum tetanic force produced by EDL and soleus muscles, and polyethylene glycol-tagged Cu,Zn-SOD decreased the maximum force production by the EDL muscles.
Negative_regulation (decreased) of Gene_expression (produced) of EDL in EDL
5) Confidence 0.05 Published 2010 Journal American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Section Abstract Doc Link PMC2806206 Disease Relevance 0 Pain Relevance 0

General Comments

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