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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.52
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Fkbp1a) protein folding (Fkbp1a) cytosol (Fkbp1a)
signal transduction (Fkbp1a) enzyme binding (Fkbp1a) cytoplasm (Fkbp1a)
Anatomy Link Frequency
muscle 1
Fkbp1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 7 98.66 Very High Very High Very High
Inflammation 54 88.08 High High
interstitial cystitis 1 79.44 Quite High
substance P 14 5.00 Very Low Very Low Very Low
Eae 5 5.00 Very Low Very Low Very Low
Inflammatory stimuli 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 95 99.28 Very High Very High Very High
INFLAMMATION 66 98.48 Very High Very High Very High
Cancer 9 86.84 High High
Metastasis 1 86.08 High High
Interstitial Cystitis 1 79.44 Quite High
Pressure And Volume Under Development 3 74.96 Quite High
Apoptosis 26 67.44 Quite High
Disease 32 50.00 Quite Low
Muscle Disease 10 50.00 Quite Low
Adhesions 2 20.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results indicated that several genes known to be part of the inflammatory response were found downstream of PAR1 activation (b2m, ccl7, cd200, cd63, cdbpd, cfl1, dusp1, fkbp1a, fth1, hspb1, marcksl1, mmp2, myo5a, nfkbia, pax1, plaur, ppia, ptpn1, ptprcap, s100a10, sim2, and tnfaip2).
Gene_expression (cdbpd) of fkbp1a associated with inflammatory response
1) Confidence 0.32 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853107 Disease Relevance 0.86 Pain Relevance 0.34
The mutant knock-in muscle sections revealed strong expression of FK1 and TDP-43 (Figure 4D–F) as compared to the wild-type controls (Figure 4A–C).
Gene_expression (expression) of FK1 in muscle associated with targeted disruption
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 0.66 Pain Relevance 0

General Comments

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