INT207088

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Context Info
Confidence 0.35
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.48
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptpn1) cytosol (Ptpn1) endoplasmic reticulum (Ptpn1)
Ptpn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 7 96.96 Very High Very High Very High
Inflammation 57 93.68 High High
interstitial cystitis 1 85.04 High High
aspirin 1 75.36 Quite High
agonist 61 5.00 Very Low Very Low Very Low
substance P 14 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Inflammatory stimuli 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Gain 12 98.44 Very High Very High Very High
INFLAMMATION 70 96.78 Very High Very High Very High
Metabolic Disorder 25 96.00 Very High Very High Very High
Interstitial Cystitis 1 85.04 High High
Cancer 13 83.44 Quite High
Metastasis 1 82.68 Quite High
Obesity 59 78.72 Quite High
Insulin Resistance 13 77.04 Quite High
Diabetes Mellitus 10 28.76 Quite Low
Adhesions 2 25.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because PTP1B
Localization (Because) of PTP1B
1) Confidence 0.35 Published 2008 Journal PPAR Research Section Body Doc Link PMC2430035 Disease Relevance 0.67 Pain Relevance 0.04
Our results indicated that several genes known to be part of the inflammatory response were found downstream of PAR1 activation (b2m, ccl7, cd200, cd63, cdbpd, cfl1, dusp1, fkbp1a, fth1, hspb1, marcksl1, mmp2, myo5a, nfkbia, pax1, plaur, ppia, ptpn1, ptprcap, s100a10, sim2, and tnfaip2).
Localization (ppia) of ptpn1 associated with inflammatory response
2) Confidence 0.17 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853107 Disease Relevance 0.81 Pain Relevance 0.32

General Comments

This test has worked.

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