INT207089

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 2
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (F2r) plasma membrane (F2r) signal transducer activity (F2r)
F2r (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 110 97.76 Very High Very High Very High
Inflammatory stimuli 15 85.76 High High
substance P 20 84.44 Quite High
Inflammatory response 18 79.76 Quite High
cytokine 2 77.08 Quite High
interstitial cystitis 2 41.00 Quite Low
agonist 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
c fibre 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystitis 18 98.12 Very High Very High Very High
INFLAMMATION 140 97.76 Very High Very High Very High
Pressure And Volume Under Development 4 77.12 Quite High
Injury 11 63.48 Quite High
Interstitial Cystitis 2 41.00 Quite Low
Neurogenic Inflammation 2 33.56 Quite Low
Carcinoma 12 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low
Overactive Bladder 10 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It remains to be determined whether or not mechanisms targeting PAR1 gene silencing or PAR1 blockade will ameliorate the clinical manifestations of cystitis.



Spec (whether) Regulation (targeting) of Spec (whether) Negative_regulation (blockade) of PAR1 associated with cystitis
1) Confidence 0.17 Published 2007 Journal BMC Physiol Section Abstract Doc Link PMC1853108 Disease Relevance 0.79 Pain Relevance 0.32
It remains to be determined whether or not mechanisms targeting PAR1 gene silencing or PAR1 blockade will ameliorate the clinical manifestation of cystitis.



Spec (whether) Regulation (targeting) of Spec (whether) Negative_regulation (blockade) of PAR1 associated with cystitis
2) Confidence 0.17 Published 2007 Journal BMC Physiol Section Abstract Doc Link PMC1853107 Disease Relevance 0.69 Pain Relevance 0.31

General Comments

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