INT207103

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pawr) nucleus (Pawr) enzyme binding (Pawr)
cytoplasm (Pawr)
Anatomy Link Frequency
bladder 4
Pawr (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 20 99.52 Very High Very High Very High
Inflammatory stimuli 15 99.02 Very High Very High Very High
Inflammatory response 18 97.98 Very High Very High Very High
Inflammation 110 92.24 High High
Potency 1 77.92 Quite High
c fibre 2 77.80 Quite High
agonist 4 40.40 Quite Low
Pain 2 17.00 Low Low
ketamine 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 140 98.86 Very High Very High Very High
Cystitis 18 84.64 Quite High
Overactive Bladder 10 66.44 Quite High
Carcinoma 12 41.44 Quite Low
Cancer 12 33.32 Quite Low
Apoptosis 2 31.04 Quite Low
Death 2 29.76 Quite Low
Pain 2 17.00 Low Low
Disease 5 16.08 Low Low
Hematological Disease 2 15.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additional evidence for the participation of PARs in the bladder inflammatory response was the finding that known pro-inflammatory stimuli such as LPS, substance P, and antigen challenge induce an increase in PAR4 RNA within four hours [20].
Positive_regulation (induce) of Positive_regulation (increase) of PAR4 in bladder associated with inflammatory response, substance p and inflammatory stimuli
1) Confidence 0.36 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853107 Disease Relevance 0.66 Pain Relevance 0.40
Additional evidence for the participation of PARs in the bladder inflammatory response was the finding that known pro-inflammatory stimuli such as LPS, substance P, and antigen challenge induce an increase in PAR4 RNA within four hours [32].
Positive_regulation (induce) of Positive_regulation (increase) of PAR4 in bladder associated with inflammatory response, substance p and inflammatory stimuli
2) Confidence 0.20 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853108 Disease Relevance 0.78 Pain Relevance 0.45

General Comments

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