INT207142

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Spg21) nucleus (Spg21) biological_process (Spg21)
cytoplasm (Spg21)
Anatomy Link Frequency
mast cell 1
Spg21 (Mus musculus)
Par2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 2 93.60 High High
Inflammation 56 72.64 Quite High
Inflammatory response 11 58.00 Quite High
Inflammatory stimuli 10 23.84 Low Low
substance P 6 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
c fibre 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 89.16 High High
Cystitis 12 80.64 Quite High
Vasculitis 1 73.36 Quite High
Carcinoma 12 70.28 Quite High
INFLAMMATION 74 58.00 Quite High
Encephalitis 1 48.00 Quite Low
Overactive Bladder 7 41.64 Quite Low
Infection 2 36.76 Quite Low
Injury 5 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regarding the difference of response between PAR1 -/- and PAR2 -/- mice, this may reflect a different role of the endogenous ligand since PAR1 is activated by thrombin, while PAR2 is activated by mast cell tryptase [23].
mast Positive_regulation (activated) of PAR2 in mast cell
1) Confidence 0.02 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853108 Disease Relevance 0.48 Pain Relevance 0.17

General Comments

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