INT207183

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 10
Disease Relevance 16.24
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Bmi1) nucleus (Bmi1) cytoplasm (Bmi1)
Anatomy Link Frequency
plasma 1
Bmi1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 40 98.52 Very High Very High Very High
corticosteroid 80 97.52 Very High Very High Very High
Inflammation 110 83.72 Quite High
Nicotine 10 16.48 Low Low
cytokine 10 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Angina 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 860 100.00 Very High Very High Very High
Asthma 540 98.96 Very High Very High Very High
Occupational Lung Diseases 290 97.84 Very High Very High Very High
Nicotine Addiction 90 97.28 Very High Very High Very High
Stress 150 95.96 Very High Very High Very High
Overweight 40 94.38 High High
INFLAMMATION 110 83.72 Quite High
Gastroesophageal Reflux Disease 40 71.68 Quite High
Apnoea 20 71.32 Quite High
Disease 50 67.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results are similar to the findings from Barros et al, that showed a negative association between BMI and exhaled NO (r2 = -0.32 vs. r2 = -0.35 in our study) in 297 non-smoking asthmatics with a mean BMI of 26 (95% C.I. 25.4 – 26.5) after controlling for potential confounders [23].
BMI Neg (negative) Binding (association) of associated with nicotine addiction, obesity and occupational lung diseases
1) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 2.30 Pain Relevance 0.15
Our data support this hypothesis by showing a significant association of BMI with exhaled 8-isoprostanes.
BMI Binding (association) of associated with obesity
2) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.53 Pain Relevance 0.07
Also, BMI is associated with increased exhaled 8-isoprostanes.
BMI Binding (associated) of associated with obesity
3) Confidence 0.01 Published 2007 Journal Respir Res Section Abstract Doc Link PMC1855924 Disease Relevance 1.07 Pain Relevance 0
Sixth, although obese and overweight subjects had higher mean Juniper ACQ, we were not able to detect meaningful differences in asthma severity across BMI categories, given the size of patient population; however, our intention was to minimize differences in asthma severity across BMI categories, to assure that the association between BMI and airway biomarkers were not biased by differences in asthma severity.
BMI Binding (association) of associated with asthma, obesity and overweight
4) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.58 Pain Relevance 0.12
In addition, BMI has been associated with higher levels of plasma and urinary levels of 8-isprostanes in men and women [38,39].
BMI Binding (associated) of in plasma associated with obesity
5) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.39 Pain Relevance 0.10
Association of BMI with exhaled NO and exhaled 8-isoprostanes
BMI Binding (Association) of associated with obesity
6) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.51 Pain Relevance 0.19
In contrast, our results showed that exhaled NO was inversely associated with BMI, after adjusting for potential confounders in stable asthmatics.
BMI Binding (associated) of associated with obesity and occupational lung diseases
7) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 2.30 Pain Relevance 0.15
BMI was inversely associated with exhaled log-NO in univariate (?
BMI Binding (associated) of associated with obesity
8) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.44 Pain Relevance 0.18
In summary, this study shows that in asthmatics, in the absence of an exacerbation, BMI and the leptin/adiponectin ratio are associated with reduced exhaled NO, and BMI is associated with increased exhaled 8-isoprostanes, possibly reflecting an increase in baseline airway oxidative stress.
BMI Binding (associated) of associated with stress, obesity and occupational lung diseases
9) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.64 Pain Relevance 0.04
However, in the study by Barros et al [23], the association between BMI and exhaled NO was not attenuated when adjusting for inhaled corticosteroids.
BMI Binding (association) of associated with corticosteroid and obesity
10) Confidence 0.01 Published 2007 Journal Respir Res Section Body Doc Link PMC1855924 Disease Relevance 1.48 Pain Relevance 0.14

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