INT207229
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Another possibility is that hemorphins, known to be produced after enzymatic cleavage of hemoglobin, are responsible for behavioral alterations. | |||||||||||||||
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samples such as phenols, bile salts, degradation products of hemoglobin, and | |||||||||||||||
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Hemoglobin degradation products such as deoxyhemoglobin, methemoglobin, and hemosiderin appear to mediate the blood-induced damage. | |||||||||||||||
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Transfusion requirements are normally determined on the basis of a patientÂ’s hemoglobin level, but a rough approximation of the increased iron load can be estimated if one assumes that splenectomized patients might receive about 120 mL red blood cells (RBC)/kg each year, and non-splenectomized patients, who tend to have greater requirements, of about 160 mL RBC/kg each year because of enhanced degradation by overactive spleens (Thalassemia International Federation Guidelines 2000). | |||||||||||||||
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