INT207233

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Context Info
Confidence 0.48
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.56
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (KRAS) mitochondrion (KRAS) plasma membrane (KRAS)
GTPase activity (KRAS)
KRAS (Homo sapiens)
Pain Link Frequency Relevance Heat
amygdala 2 61.72 Quite High
palliative 2 5.00 Very Low Very Low Very Low
Endogenous opioid 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Dynorphin 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
opioid receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometrial Hyperplasia 4 99.84 Very High Very High Very High
Endometrial Cancer 153 96.80 Very High Very High Very High
Cancer 101 96.56 Very High Very High Very High
Microsatellite Instability 47 95.16 Very High Very High Very High
Carcinoma 61 94.68 High High
Familial Adenomatous Polyposis 1 58.48 Quite High
Adenocarcinoma 6 56.16 Quite High
Endometroid Carcinoma 21 50.76 Quite High
Colon Cancer 22 50.00 Quite Low
Death 3 31.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
KRAS mutations were detected in endometrial hyperplasias at a similar rate to that observed in endometrioid endometrial carcinomas, suggesting that KRAS mutations are early events in endometrial carcinogensis [9, 13].
Transcription (detected) of KRAS associated with endometrial hyperplasia and endometrial cancer
1) Confidence 0.48 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 1.31 Pain Relevance 0
KRAS mutations were detected in 192 patients (35.6%).
Transcription (detected) of KRAS
2) Confidence 0.42 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886318 Disease Relevance 0.24 Pain Relevance 0
For the mtDNA analysis, DNA was extracted from 29 NS, 23 S, 23 Cross (16 F1 + 7 backcrosses) and 12 wild foxes.
Transcription (extracted) of NS
3) Confidence 0.25 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1858698 Disease Relevance 0 Pain Relevance 0.03

General Comments

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