INT207259

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.94
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CNBP, TXNIP) nucleus (CNBP, TXNIP) cytoplasm (CNBP, TXNIP)
endoplasmic reticulum (CNBP) cell cycle (TXNIP) DNA binding (CNBP)
CNBP (Homo sapiens)
TXNIP (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 18 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 112 100.00 Very High Very High Very High
Insulin Resistance 24 95.88 Very High Very High Very High
Obesity 34 71.92 Quite High
Toxicity 10 57.44 Quite High
Prediabetic State 14 18.64 Low Low
Impaired Glucose Tolerance 16 5.00 Very Low Very Low Very Low
Parkinson's Disease 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Hyperglycemia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To study the association between TXNIP variants and T2DM, nine tag SNPs and two missense SNPs were genotyped in ?
T2DM Binding (association) of TXNIP associated with diabetes mellitus
1) Confidence 0.01 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1858708 Disease Relevance 0.24 Pain Relevance 0
Although we did not detect polymorphisms in TXNIP that are associated with T2DM, it is still formally possible that inherited variation in other genes in the TNXIP pathway may predispose to the risk of developing T2DM.


T2DM Binding (associated) of TXNIP associated with diabetes mellitus
2) Confidence 0.00 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1858708 Disease Relevance 0.70 Pain Relevance 0

General Comments

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