INT207299

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.50
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (BCL6) nucleolus (BCL6) nucleus (BCL6)
intracellular (BCL6)
BCL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 34 97.92 Very High Very High Very High
Inflammatory response 6 96.08 Very High Very High Very High
agonist 40 88.88 High High
chemokine 5 56.96 Quite High
cytokine 4 50.52 Quite High
imagery 4 50.00 Quite Low
Arthritis 2 45.64 Quite Low
tolerance 9 42.32 Quite Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
B-cell Lymphoma 28 99.72 Very High Very High Very High
INFLAMMATION 39 97.92 Very High Very High Very High
Mantle-cell Lymphoma 59 95.28 Very High Very High Very High
Targeted Disruption 15 91.84 High High
Lymphatic System Cancer 220 91.12 High High
Disease 46 88.04 High High
Diffuse Large B-cell Lymphoma 68 88.00 High High
B-cell Chronic Lymphocytic Leukemia 9 86.00 High High
Repression 9 81.44 Quite High
Htlv Types I And Ii 1 80.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BCL6 has also been reported to interact with PPAR?
BCL6 Binding (interact) of
1) Confidence 0.30 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1858708 Disease Relevance 0.10 Pain Relevance 0
Uccella et al. used the most common approach with CD10, Bcl-2, BCL6, and MUM1 antibodies in 71 patients and could not find prognostic relevance, although BCL6 expression as single marker was [61].
BCL6 Binding (approach) of
2) Confidence 0.13 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 0.61 Pain Relevance 0.03
However, Bcl-6, alone and in the context of a GC phenotype, appeared to be associated with a favorable prognosis.
Bcl-6 Spec (appeared) Binding (associated) of
3) Confidence 0.09 Published 2009 Journal Rare Tumors Section Body Doc Link PMC2994446 Disease Relevance 0.50 Pain Relevance 0
binds to corepressor molecules including Bcl-6,
Bcl-6 Binding (binds) of
4) Confidence 0.08 Published 2008 Journal PPAR Research Section Body Doc Link PMC2423003 Disease Relevance 0.48 Pain Relevance 0.20
-bound Bcl-6 is also released and is free to
Bcl-6 Binding (free) of
5) Confidence 0.06 Published 2008 Journal PPAR Research Section Body Doc Link PMC2423003 Disease Relevance 0.44 Pain Relevance 0.18
The cells express relatively intense surface immunoglobulin M (IgM) and/or immunoglobulin D (IgD) and are usually positive for CD5, FMC7 and CD43, but negative for CD10 and BCL6.
BCL6 Binding (negative) of
6) Confidence 0.04 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2853553 Disease Relevance 1.37 Pain Relevance 0

General Comments

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