INT207356

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYP27A1) small molecule metabolic process (CYP27A1) plasma membrane (PTGER2)
signal transducer activity (PTGER2)
PTGER2 (Homo sapiens)
CYP27A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 13 65.04 Quite High
cINOD 10 25.00 Low Low
Inflammation 5 25.00 Low Low
Pain 3 25.00 Low Low
Arthritis 1 25.00 Low Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
diclofenac 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerotic Plaque 3 54.24 Quite High
Atherosclerosis 9 39.72 Quite Low
Myocardial Infarction 8 25.00 Low Low
INFLAMMATION 7 25.00 Low Low
Pain 3 25.00 Low Low
Arthritis 1 25.00 Low Low
Thrombosis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Stroke 3 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reversal of inhibitory effects on 27-hydroxylase and ABCA1 expression by PGD2 and PGE2 suggests involvement of their respective signaling pathways.
PGE2 Regulation (effects) of Gene_expression (expression) of 27-hydroxylase
1) Confidence 0.00 Published 2007 Journal Arthritis Res Ther Section Abstract Doc Link PMC1860062 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

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