INT207375

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
cytoplasm (CPOX)
CPOX (Homo sapiens)
Chol1 (Mus musculus)
Pain Link Frequency Relevance Heat
diclofenac 1 60.12 Quite High
cINOD 10 59.28 Quite High
COX-2 inhibitor 13 53.20 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 9 93.08 High High
Myocardial Infarction 8 63.48 Quite High
INFLAMMATION 7 58.72 Quite High
Stroke 3 36.28 Quite Low
Heart Disease 1 35.84 Quite Low
Adenomatous Polyps 1 9.52 Low Low
Thrombosis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data demonstrate that pharmacological inhibition of COX reduces expression of the cholesterol-metabolizing enzyme cholesterol 27-hydroxylase and the cholesterol transport protein ABCA1.
Negative_regulation (inhibition) of COX Negative_regulation (reduces) of Gene_expression (expression) of cholesterol
1) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860062 Disease Relevance 0.37 Pain Relevance 0.17

General Comments

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