INT207396

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, Tnfsf11) extracellular region (IL6, Tnfsf11) cell differentiation (Tnfsf11)
aging (IL6) plasma membrane (Tnfsf11) intracellular (Tnfsf11)
IL6 (Homo sapiens)
Tnfsf11 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 34 100.00 Very High Very High Very High
cytokine 5 99.16 Very High Very High Very High
Inflammation 30 98.76 Very High Very High Very High
Arthritis 19 95.36 Very High Very High Very High
metalloproteinase 2 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 34 100.00 Very High Very High Very High
INFLAMMATION 26 98.76 Very High Very High Very High
Arthritis 19 95.36 Very High Very High Very High
Seronegative Spondarthritis 2 92.64 High High
Necrosis 2 86.36 High High
Cancer 3 86.00 High High
Hypercalcemia 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Arthropathy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, IL-1, IL-6 and IL-17, which are abundant in the synovial membrane of RA patients and increase RANKL expression.
IL-6 Positive_regulation (increase) of Gene_expression (expression) of RANKL associated with rheumatoid arthritis
1) Confidence 0.03 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860063 Disease Relevance 0.95 Pain Relevance 0.51

General Comments

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