INT207409

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger2, Tacr1) signal transducer activity (Ptger2, Tacr1) response to stress (Tacr1)
cytoplasm (Tacr1)
Ptger2 (Rattus norvegicus)
Tacr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 107 100.00 Very High Very High Very High
b2 receptor 10 92.80 High High
Arthritis 28 75.52 Quite High
Pain 11 50.00 Quite Low
bradykinin 40 5.00 Very Low Very Low Very Low
Inflammation 33 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
IPN 3 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Nerve growth factor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 107 100.00 Very High Very High Very High
Arthritis 30 75.52 Quite High
Pain 10 50.00 Quite Low
INFLAMMATION 33 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Arthralgia 3 5.00 Very Low Very Low Very Low
Inflammatory Pain 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because we previously found that the expression of NK1 receptor-like IR in DRG neurones is upregulated by long-term addition of either PGE2 [43] or IL-6 [46] to the culture medium, we measured the concentration of PGE2 and IL-6 in the supernatants from different cultures, and we tested whether interference of PGE2 and IL-6 would reduce the effect of FLS cells on NK1 receptor expression in DRG neurones.
PGE2 Positive_regulation (upregulated) of Gene_expression (expression) of NK1 receptor associated with dorsal root ganglion
1) Confidence 0.04 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860064 Disease Relevance 0.56 Pain Relevance 0.32

General Comments

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