INT207437

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.64
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ERAL1) extracellular space (PLA2G7) extracellular region (PLA2G7)
RNA binding (ERAL1) rRNA binding (ERAL1) intracellular (ERAL1)
Anatomy Link Frequency
plasma 3
PLA2G7 (Homo sapiens)
ERAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 224 100.00 Very High Very High Very High
methotrexate 12 64.04 Quite High
Inflammation 36 48.32 Quite Low
Inflammatory marker 8 11.96 Low Low
addiction 4 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 224 100.00 Very High Very High Very High
Disease 52 97.32 Very High Very High Very High
Disorder Of Lipid Metabolism 172 96.64 Very High Very High Very High
Repression 8 83.92 Quite High
Cancer 4 65.92 Quite High
Necrosis 4 65.44 Quite High
INFLAMMATION 44 48.32 Quite Low
Atherosclerosis 32 46.56 Quite Low
Anti-phospholipid Antibody Syndrome 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study further shows that the low Lp-PLA2 activity is independently associated with ERA.
Lp-PLA2 Binding (associated) of ERA associated with rheumatoid arthritis
1) Confidence 0.14 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 0.74 Pain Relevance 0.26
The low plasma Lp-PLA2 activity and the increased titers against oxLDLD are independently associated with ERA, suggesting an important role of these parameters in the pathophysiology of ERA.
plasma Lp-PLA2 Binding (associated) of ERA in plasma associated with rheumatoid arthritis
2) Confidence 0.14 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 1.62 Pain Relevance 0.28
The results of this analysis showed that only autoantibody titers against all types of oxLDL as well as the low plasma Lp-PLA2 activity are associated with ERA (Table 3).
plasma Lp-PLA2 Binding (associated) of ERA in plasma associated with rheumatoid arthritis
3) Confidence 0.12 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 0.79 Pain Relevance 0.33
Multivariate regression analysis showed that the elevated autoantibody titers towards oxLDL at the end of the decomposition phase of oxidation and the low plasma Lp-PLA2 activity are independently associated with ERA.
plasma Lp-PLA2 Binding (associated) of ERA in plasma associated with rheumatoid arthritis
4) Confidence 0.12 Published 2007 Journal Arthritis Res Ther Section Abstract Doc Link PMC1860077 Disease Relevance 0.48 Pain Relevance 0.24

General Comments

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