INT207443

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.69
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ERAL1) RNA binding (ERAL1) rRNA binding (ERAL1)
intracellular (ERAL1) ribosome biogenesis (ERAL1)
ERAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 195 100.00 Very High Very High Very High
Arthritis 45 100.00 Very High Very High Very High
Osteoarthritis 32 96.96 Very High Very High Very High
spinal inflammation 2 81.84 Quite High
cytokine 9 72.52 Quite High
addiction 2 31.00 Quite Low
Leflunomide 15 25.00 Low Low
Inflammation 32 23.52 Low Low
Inflammatory marker 4 6.88 Low Low
methotrexate 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 240 100.00 Very High Very High Very High
Arthritis 11 100.00 Very High Very High Very High
Frailty 34 96.96 Very High Very High Very High
Obesity 7 96.24 Very High Very High Very High
Repression 4 94.96 High High
Juvenile Chronic Polyarthritis 35 82.64 Quite High
Low Back Pain 2 81.84 Quite High
Necrosis 3 76.28 Quite High
Cancer 6 75.92 Quite High
Disorder Of Lipid Metabolism 86 73.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
to the IL12A gene, showed differences in allele frequencies across the ILAR subtypes and this was driven by a strong association with ERA.
ERA Binding (association) of associated with arthritis
1) Confidence 0.19 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 0.81 Pain Relevance 0.37
Importantly, the antibody titers against oxLDLD are independently associated with ERA, thus providing evidence that such types of mildly oxLDL may be implicated in the pathophysiology of ERA.
ERA Binding (associated) of associated with rheumatoid arthritis
2) Confidence 0.14 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 0.72 Pain Relevance 0.24
In search for specific genes determining the timing of menarche Stavrou et al [32] evaluated whether the XbaI and PvuII polymorphisms of estrogen receptor a (ERa) gene are associated with the age at menarche.
ERa Binding (associated) of
3) Confidence 0.14 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2958977 Disease Relevance 0.10 Pain Relevance 0
To further identify whether these parameters could independently be associated with ERA, multivariate logistic regression analysis was performed, taking into account all statistically significant factors as they derived from univariate analysis.
ERA Binding (associated) of associated with rheumatoid arthritis
4) Confidence 0.13 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 0.82 Pain Relevance 0.35
PBMCs were isolated from individuals diagnosed with early RA (ERA) (n?
ERA Binding (diagnosed) of associated with rheumatoid arthritis
5) Confidence 0.04 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2724743 Disease Relevance 1.24 Pain Relevance 0.50

General Comments

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