INT207453

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ERAL1) RNA binding (ERAL1) rRNA binding (ERAL1)
intracellular (ERAL1) ribosome biogenesis (ERAL1)
Anatomy Link Frequency
macrophages 1
ERAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 56 100.00 Very High Very High Very High
Inflammation 9 100.00 Very High Very High Very High
addiction 1 88.88 High High
methotrexate 3 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 56 100.00 Very High Very High Very High
INFLAMMATION 11 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 43 96.36 Very High Very High Very High
Necrosis 1 75.52 Quite High
Cancer 1 75.16 Quite High
Disease 13 53.12 Quite High
Atherosclerosis 8 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Anti-phospholipid Antibody Syndrome 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We may consequently suggest that the low levels of enzyme activity in the plasma of ERA patients at baseline could be the combined effect of the inflammation-induced reduction of enzyme secretion from macrophages and the expected increase in plasma enzyme levels due to the elevation of LDL-cholesterol in plasma of ERA patients.
Localization (secretion) of ERA in macrophages associated with inflammation and rheumatoid arthritis
1) Confidence 0.28 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 0.89 Pain Relevance 0.34

General Comments

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