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Context Info
Confidence 0.09
First Reported 1990
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
tooth 1
Dspp (Mus musculus)
Pain Link Frequency Relevance Heat
Clonidine 11 100.00 Very High Very High Very High
Pain 1 99.08 Very High Very High Very High
noradrenaline 2 92.40 High High
Spinal cord 2 75.00 Quite High
Antinociceptive 2 75.00 Quite High
Calcium channel 1 63.12 Quite High
intrathecal 1 62.48 Quite High
tail-flick 1 59.12 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 1 99.08 Very High Very High Very High
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, for the DSP4 treated animals the down-regulation of 3H-clonidine binding induced by 10(-4) M Gpp(NH)p was significantly higher than for control mice.
DSP4 Binding (binding) of associated with clonidine
1) Confidence 0.09 Published 1990 Journal Pharmacol. Toxicol. Section Abstract Doc Link 2156247 Disease Relevance 0 Pain Relevance 1.13
Based on the hypothesis that the primary cilium is crucial both for dentin formation and possibly in tooth pain transmission, we have investigated the expression and localization of the main cilium components and involvement of the OFD1 gene in tooth morphogenesis.
dentin Binding (formation) of in tooth associated with pain
2) Confidence 0.03 Published 2009 Journal J. Dent. Res. Section Abstract Doc Link 19783798 Disease Relevance 0.10 Pain Relevance 0.13

General Comments

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