INT207529

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tfap2a) Golgi apparatus (Tfap2a) nucleus (Tfap2a)
DNA binding (Tfap2a) transcription factor binding (Tfap2a) cytoplasm (Tfap2a)
Tfap2a (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 84 98.64 Very High Very High Very High
opioid receptor 5 90.44 High High
agonist 25 63.64 Quite High
opiate 1 63.28 Quite High
Morphine 2 58.96 Quite High
analgesia 1 52.80 Quite High
Opioid 2 50.88 Quite High
Endogenous opioid 1 49.92 Quite Low
Potency 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 138 71.64 Quite High
Targeted Disruption 2 61.28 Quite High
Repression 9 50.00 Quite Low
Cancer 5 50.00 Quite Low
Contagious Ecthyma 14 35.20 Quite Low
Diabetes Mellitus 10 5.00 Very Low Very Low Very Low
Liver Cancer 3 5.00 Very Low Very Low Very Low
Neuroblastoma 2 5.00 Very Low Very Low Very Low
Retinoblastoma 1 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our laboratory and others have demonstrated that MOR promoter activity is regulated by many enhancer elements and their related transcriptional factors such as SOX, SP1, AP2, NF-?
Localization (related) of AP2 associated with mu opioid receptor
1) Confidence 0.34 Published 2007 Journal Nucleic Acids Research Section Body Doc Link PMC1865057 Disease Relevance 0.06 Pain Relevance 0.60
Primers/probe ABI identifiers for mouse studies were Tusc5 (Mm00624784_m1), aP2/FABP4 (Mm00445880_m1), PPAR?
Localization (were) of aP2
2) Confidence 0.06 Published 2009 Journal PPAR Research Section Body Doc Link PMC2830574 Disease Relevance 0.07 Pain Relevance 0

General Comments

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