INT207535

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.98
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tfap2a) Golgi apparatus (Tfap2a) nucleus (Tfap2a)
DNA binding (Tfap2a) transcription factor binding (Tfap2a) cytoplasm (Tfap2a)
Tfap2a (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 84 98.48 Very High Very High Very High
opioid receptor 5 90.12 High High
Inflammation 20 74.16 Quite High
cINOD 9 69.44 Quite High
agonist 5 63.32 Quite High
opiate 1 62.96 Quite High
Morphine 2 58.64 Quite High
analgesia 1 52.48 Quite High
Opioid 2 50.56 Quite High
Endogenous opioid 1 49.60 Quite Low
Disease Link Frequency Relevance Heat
Hypoxia 32 80.40 Quite High
Disease 167 78.32 Quite High
Stress 57 75.52 Quite High
INFLAMMATION 26 74.16 Quite High
Targeted Disruption 66 66.88 Quite High
Death 15 55.68 Quite High
Repression 10 50.00 Quite Low
Contagious Ecthyma 16 35.20 Quite Low
Parkinson's Disease 3 13.44 Low Low
Alzheimer's Dementia 51 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our laboratory and others have demonstrated that MOR promoter activity is regulated by many enhancer elements and their related transcriptional factors such as SOX, SP1, AP2, NF-?
Transcription (transcriptional) of AP2 associated with mu opioid receptor
1) Confidence 0.31 Published 2007 Journal Nucleic Acids Research Section Body Doc Link PMC1865057 Disease Relevance 0.06 Pain Relevance 0.60
It also contains a variety of transcription factor binding sites, including those for Sp1, GATA-1, AP1, AP2, CREB, estrogen and glucocorticoid receptors, NF?
Transcription (transcription) of AP2
2) Confidence 0.07 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 0.56 Pain Relevance 0
It also contains a variety of transcription factor binding sites, including those for Sp1, GATA-1, AP1, AP2, CREB, estrogen and glucocorticoid receptors, NF?
Transcription (transcription) of AP2
3) Confidence 0.06 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2211305 Disease Relevance 0.36 Pain Relevance 0.14

General Comments

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