INT207634

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkca, Mapk1) protein complex (Prkca, Mapk1) cytoplasm (Prkca, Mapk1)
cytosol (Prkca, Mapk1) nucleus (Prkca, Mapk1) kinase activity (Prkca, Mapk1)
Prkca (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 21 100.00 Very High Very High Very High
cytokine 2 54.00 Quite High
Hippocampus 5 5.00 Very Low Very Low Very Low
long-term potentiation 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 5 52.56 Quite High
Neuroblastoma 3 50.00 Quite Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Starvation 2 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results in the mutant S36A, which abolished the phosphorylation of Ng by PKC, indicated that the basal level of ERK activity was increased even before PMA treatment, suggesting the phosphorylation of Ng by PKC inhibited ERK activation.
PKC Negative_regulation (inhibited) of Positive_regulation (activation) of ERK associated with kinase c
1) Confidence 0.08 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1865092 Disease Relevance 0.10 Pain Relevance 0.28

General Comments

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