INT207668

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrnb4) plasma membrane (Chrnb4)
Chrnb4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 1 54.64 Quite High
sodium channel 2 50.56 Quite High
addiction 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 18 50.00 Quite Low
Heart Rate Under Development 19 48.96 Quite Low
Coronary Heart Disease 3 37.52 Quite Low
Sprains And Strains 18 22.28 Low Low
Disease 6 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Syncope 1 5.00 Very Low Very Low Very Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gene ontology analysis then revealed that most of the 65 known genes were related to "metal ion binding", "protein binding", or "synaptic transmission" functions, and some of these presented "receptor/transporter/channel activity", some of which have an ion channel activity (Chrna5, Chrna3, Chrnb4, Htr3a, Htr3b, Fxyd2, and Hcn4).
Chrnb4 Binding (binding) of
1) Confidence 0.27 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1865373 Disease Relevance 0 Pain Relevance 0.05

General Comments

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