INT207729

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (FGFR2) Golgi apparatus (FGFR2) cytoplasmic membrane-bounded vesicle (FGFR2)
plasma membrane (FGFR2) nucleus (FGFR2) cell-cell signaling (FGFR2)
Anatomy Link Frequency
fibroblast 2
FGFR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 49.08 Quite Low
Immobilon 1 29.84 Quite Low
ischemia 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Snapping jaw 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometrial Cancer 134 96.52 Very High Very High Very High
Prostate Cancer 55 90.52 High High
Uterine Cancer 4 89.12 High High
Cancer 156 84.80 Quite High
Wound Healing 16 80.40 Quite High
Metastasis 53 66.20 Quite High
Microsatellite Instability 30 55.64 Quite High
Adhesions 13 52.84 Quite High
Metaplasia 2 41.76 Quite Low
Endometrial Hyperplasia 4 32.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For evaluation of immunohistochemical results, the relative intensities of immunostaining for KGF and KGFR were evaluated as negative (?)
Regulation (intensities) of KGFR
1) Confidence 0.22 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2896696 Disease Relevance 0.08 Pain Relevance 0
Alterations in the fibroblast growth factor receptor 2 (FGFR2) gene causes the receptors to become active, leading to cell proliferation.
Regulation (Alterations) of FGFR2 in fibroblast
2) Confidence 0.21 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2852605 Disease Relevance 0.88 Pain Relevance 0
Alterations in the fibroblast growth factor receptor 2 (FGFR2) gene causes the receptors to become active, leading to cell proliferation.
Regulation (Alterations) of fibroblast growth factor receptor 2 in fibroblast
3) Confidence 0.21 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2852605 Disease Relevance 0.88 Pain Relevance 0
The regulated genes include DUSP1, DUSP2, DUSP8, MAP3K8, MAP4K4, FGF13, FGFR2 and FOS.
Regulation (regulated) of FGFR2
4) Confidence 0.16 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1865555 Disease Relevance 0.50 Pain Relevance 0

General Comments

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