INT207739

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.11
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FBN1) extracellular region (FBN1) proteinaceous extracellular matrix (FBN1)
FBN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 3 57.52 Quite High
medulla 1 56.56 Quite High
ischemia 4 39.92 Quite Low
Inflammation 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 2 98.50 Very High Very High Very High
Cancer 72 96.48 Very High Very High Very High
Marfan Syndrome 2 92.72 High High
Disease 13 88.68 High High
Prostate Cancer 55 84.00 Quite High
Congenital Anomalies 5 84.00 Quite High
Metastasis 52 81.24 Quite High
Esophageal Atresia 1 78.88 Quite High
Hypertension 3 68.28 Quite High
Stress 1 66.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FBN, also representative of the EMT transition [38] is overexpressed in our metastatic samples.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of FBN
1) Confidence 0.22 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1865555 Disease Relevance 1.10 Pain Relevance 0.03
Mutations in fibrillin 1 lead to Marfan's syndrome, in which major defects affect the vascular structures, in agreement with vascular SMC expression of fibrillin-1 (Figure 2B).
Positive_regulation (vascular) of Gene_expression (expression) of fibrillin-1 associated with syndrome
2) Confidence 0.16 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 1.01 Pain Relevance 0.03

General Comments

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