INT207837

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GAD2) lyase activity (GAD2) Golgi apparatus (GAD2)
cytoplasmic membrane-bounded vesicle (GAD2) plasma membrane (GAD2) cytoplasm (GAD2)
GAD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 16 99.16 Very High Very High Very High
Somatostatin 6 27.52 Quite Low
conotoxin 24 5.00 Very Low Very Low Very Low
tetrodotoxin 20 5.00 Very Low Very Low Very Low
Action potential 16 5.00 Very Low Very Low Very Low
gABA 10 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 14 5.00 Very Low Very Low Very Low
Hypoglycemia 4 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 4 5.00 Very Low Very Low Very Low
Hyperinsulinism 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M inhibited glucagon secretion in parallel with an inhibition of insulin release from both mouse and rat islets (Figure 2A and 2B).
Negative_regulation (inhibition) of Localization (release) of islets
1) Confidence 0.01 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.03
The GABAA receptor antagonist SR95531 had no effect on glucose-induced inhibition of glucagon secretion from human islets, and whole-cell voltage-clamp measurements indicate that human ?
Negative_regulation (inhibition) of Localization (secretion) of islets associated with antagonist
2) Confidence 0.01 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.05

General Comments

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