INT207847

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Context Info
Confidence 0.17
First Reported 2005
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 9
Disease Relevance 7.06
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Olr1) extracellular region (Olr1) cell adhesion (Olr1)
plasma membrane (Olr1)
Anatomy Link Frequency
plasma 1
monocytes 1
extracellular matrix 1
Olr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 3 94.52 High High
Inflammatory response 16 84.72 Quite High
Inflammation 156 83.12 Quite High
cytokine 72 82.28 Quite High
bradykinin 3 72.76 Quite High
metalloproteinase 75 29.28 Quite Low
Central nervous system 1 7.64 Low Low
chemokine 21 5.00 Very Low Very Low Very Low
Angina 18 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 92 98.20 Very High Very High Very High
Apoptosis 51 98.20 Very High Very High Very High
Atherosclerotic Plaque 154 97.68 Very High Very High Very High
Disorder Of Lipid Metabolism 426 94.64 High High
Myocardial Infarction 19 92.64 High High
Atherosclerosis 385 92.56 High High
Diabetes Mellitus 20 90.08 High High
Chronic Renal Failure 3 89.52 High High
Hypertension 12 88.60 High High
Disease 80 87.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ROS, CD40 ligand, lectin-like oxidized LDL receptor-1 (LOX-1) and lipoproteins such as VLDL or oxidized-LDL (Ox-LDL) also up-regulate endothelial expression of adhesion molecules (Mach et al 1997; Libby 2002; Norata, Pirillo, et al 2003).
LOX-1 Binding (oxidized) of associated with adhesions
1) Confidence 0.17 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.00 Pain Relevance 0.16
ROS, CD40 ligand, lectin-like oxidized LDL receptor-1 (LOX-1) and lipoproteins such as VLDL or oxidized-LDL (Ox-LDL) also up-regulate endothelial expression of adhesion molecules (Mach et al 1997; Libby 2002; Norata, Pirillo, et al 2003).
Ox-LDL Binding (oxidized) of associated with adhesions
2) Confidence 0.17 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.01 Pain Relevance 0.16
ROS, CD40 ligand, lectin-like oxidized LDL receptor-1 (LOX-1) and lipoproteins such as VLDL or oxidized-LDL (Ox-LDL) also up-regulate endothelial expression of adhesion molecules (Mach et al 1997; Libby 2002; Norata, Pirillo, et al 2003).
LDL receptor-1 Binding (oxidized) of associated with adhesions
3) Confidence 0.15 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.00 Pain Relevance 0.16
In the present study we did not find any association between radical production and oxLDL in plasma.
oxLDL Neg (not) Binding (association) of in plasma
4) Confidence 0.10 Published 2007 Journal International Journal of Medical Sciences Section Body Doc Link PMC1868659 Disease Relevance 0.76 Pain Relevance 0
within the extracellular matrix of the arterial wall, interact with oxLDL via
oxLDL Binding (interact) of in extracellular matrix
5) Confidence 0.03 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.69 Pain Relevance 0.11
established that oxLDL acts as a chemoattractant for monocytes allowing them to
oxLDL Binding (chemoattractant) of in monocytes
6) Confidence 0.02 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.51 Pain Relevance 0.03
oxidation-specific epitopes present on oxLDL are also presented on the surface
oxLDL Binding (epitopes) of
7) Confidence 0.02 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.74 Pain Relevance 0.07
that IgM antibodies may bind to oxLDL preventing its binding and degradation by
oxLDL Binding (binding) of
8) Confidence 0.02 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.68 Pain Relevance 0.03
that IgM antibodies may bind to oxLDL preventing its binding and degradation by
oxLDL Binding (bind) of
9) Confidence 0.02 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.68 Pain Relevance 0.03

General Comments

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