INT207890

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.87
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
face 2
body 2
Lmrq1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 73.76 Quite High
Bioavailability 6 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cryotherapy 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 78 100.00 Very High Very High Very High
Sprains And Strains 2 99.84 Very High Very High Very High
Leishmaniasis 191 98.60 Very High Very High Very High
Disease 50 98.44 Very High Very High Very High
Cicatrix 10 93.16 High High
Toxicity 8 91.72 High High
Anaemia 3 78.08 Quite High
Neglected Diseases 12 68.80 Quite High
Death 3 41.24 Quite Low
Keloid Scars 3 40.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growth development, determined by weekly body mass measure, was not affected by the Leishmania infection and no expressive alterations of health markers were observed.
Neg (not) Regulation (affected) of Gene_expression (infection) of Leishmania in body associated with infection
1) Confidence 0.28 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2814861 Disease Relevance 0.72 Pain Relevance 0
Also, we know that some drugs and regimens are effective only against certain Leishmania species or strains and only in certain areas of the world.
Regulation (effective) of Gene_expression (species) of Leishmania associated with sprains and strains
2) Confidence 0.05 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2765639 Disease Relevance 0.79 Pain Relevance 0.07
These criteria included:

• Severity of the disease, including duration of disease, average size of lesions and number of lesions per patient and severity of scars • Lack of response to available drugs • The overall incidence and prevalence of the disease (based on available data) • Sequelae of the disease, including leishmaniasis recidivans (a long-lasting relapsing form of CL often located on the face) and mucosal disease • Public health aspects, including the impact of treatment of individuals on control of transmission of Leishmania spp, the etiological agent (s) of leishmaniasis • Lack of major efforts in drug development

Regulation (control) of Gene_expression (transmission) of Leishmania in face associated with leishmaniasis, cicatrix and disease
3) Confidence 0.03 Published 2007 Journal Kinetoplastid Biol Dis Section Body Doc Link PMC1868746 Disease Relevance 1.36 Pain Relevance 0

General Comments

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