INT20803

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Context Info
Confidence 0.57
First Reported 1990
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MYCN) DNA binding (MYCN)
MYCN (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 37 96.48 Very High Very High Very High
noradrenaline 3 93.24 High High
agonist 1 80.40 Quite High
Enkephalin 1 25.00 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Advanced Or Metastatic Breast Cancer 13 96.68 Very High Very High Very High
INFLAMMATION 27 96.48 Very High Very High Very High
Inflammatory Breast Neoplasms 134 93.24 High High
Breast Cancer 20 89.28 High High
Neuroblastoma 1 74.80 Quite High
Cancer 23 65.12 Quite High
Disease 6 33.44 Quite Low
Genomic Instability 1 14.68 Low Low
Metastasis 5 5.00 Very Low Very Low Very Low
Aggression 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 27 upregulated genes encoded seven transcription factors (JUN, EGR1, JUNB, FOS, FOSB, MYCN, and SNAIL1), four of which are components of the AP-1 transcription factor family (JUN, JUNB, FOS, and FOSB).
Transcription (transcription) of MYCN
1) Confidence 0.57 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1064141 Disease Relevance 1.12 Pain Relevance 0.09
The level of proenkephalin A mRNA increased approximately two to three times under the same drug conditions, whereas the level of N-myc mRNA did not change significantly.
Transcription (level) of N-myc
2) Confidence 0.52 Published 1990 Journal J. Mol. Endocrinol. Section Abstract Doc Link 2157452 Disease Relevance 0.07 Pain Relevance 0.16

General Comments

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