INT208039

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 4.95
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (UTS2R) plasma membrane (UTS2R) signal transducer activity (UTS2R)
Anatomy Link Frequency
cleavage 1
internal 1
UTS2R (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 1 88.16 High High
rheumatoid arthritis 1 86.00 High High
cytokine 50 41.36 Quite Low
Inflammation 44 39.76 Quite Low
Central nervous system 56 36.68 Quite Low
cerebral cortex 4 5.68 Low Low
imagery 28 5.00 Very Low Very Low Very Low
Pain 21 5.00 Very Low Very Low Very Low
Crohn's disease 16 5.00 Very Low Very Low Very Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 22 100.00 Very High Very High Very High
Contagious Ecthyma 11 96.52 Very High Very High Very High
Nasopharynx Cancer 104 94.16 High High
Systemic Lupus Erythematosus 1 93.00 High High
Cancer 258 91.36 High High
Nasal Polyps 2 90.48 High High
Disease 115 89.00 High High
Neurodegenerative Disease 36 88.40 High High
Low Back Pain 1 88.16 High High
Leukemia 11 86.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within the exon 1b of the alternative 5'-UTR region of human NOD2, three uORFs with variable lengths were identified upstream of the main ORF located in exon 2.
Gene_expression (region) of UTR associated with contagious ecthyma
1) Confidence 0.43 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2228316 Disease Relevance 0.15 Pain Relevance 0
The short alternative 5'UTR has also been found in a systematic approach characterizing transcripts, which contain alternative promoter regions (DA224866 in [14]).
Gene_expression (found) of UTR
2) Confidence 0.39 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2228316 Disease Relevance 0 Pain Relevance 0
Thus, the mutation rate at nonsynonymous, promoter, and UTR CH nucleotides is >16-fold lower than the baseline, whereas the mutation rate at repetitive and synonymous positions is ?
Gene_expression (nucleotides) of UTR CH
3) Confidence 0.24 Published 2010 Journal Molecular Biology and Evolution Section Body Doc Link PMC2872621 Disease Relevance 0 Pain Relevance 0
The rat and zebrafish Cdk5r1 3'-UTR sequences were assembled starting from the ESTs annotated in the UCSC Genome Browser (rat assembly version 3.4 (rn4) and zebrafish assembly version 6 (Zv6)) using the CAP3 sequence assembly program [64] with default parameter values.
Gene_expression (sequences) of UTR
4) Confidence 0.23 Published 2007 Journal BMC Mol Biol Section Body Doc Link PMC2222623 Disease Relevance 0.31 Pain Relevance 0
CDK5R1 3'-UTR fragments differently affect reporter gene expression
Gene_expression (fragments) of UTR
5) Confidence 0.23 Published 2007 Journal BMC Mol Biol Section Body Doc Link PMC2222623 Disease Relevance 0.11 Pain Relevance 0
-UTR polymorphism has
Gene_expression (polymorphism) of UTR
6) Confidence 0.19 Published 2007 Journal Comparative and Functional Genomics Section Body Doc Link PMC2233780 Disease Relevance 0.81 Pain Relevance 0
It is worth noting that functional AREs are present in the 3'-UTR of many cyclin mRNAs [43], raising the hypothesis that ARE-mediated post-transcriptional regulation may be a common mechanism for the control of expression in this class of genes, to which CDK5R1 belongs.
Gene_expression (expression) of UTR
7) Confidence 0.18 Published 2007 Journal BMC Mol Biol Section Body Doc Link PMC2222623 Disease Relevance 0 Pain Relevance 0
UTR, can promote cleavage and polyadenylation at such 3?
Gene_expression (promote) of UTR in cleavage
8) Confidence 0.16 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0 Pain Relevance 0
-UTR of HCV as positive control and produced an internal control DNA to verify each PCR reaction.
Gene_expression (produced) of UTR in internal associated with hepatitis c virus infection
9) Confidence 0.15 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2861168 Disease Relevance 1.20 Pain Relevance 0
In addition, target sequences of more than one miRNa species can be incorporated into 3’-UTR because miRNA expression patterns differ across normal tissue of different origins.
Gene_expression (expression) of UTR
10) Confidence 0.11 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 1.06 Pain Relevance 0
UTR, especially the base-pairing status and nucleotide context of the 3?
Gene_expression (context) of UTR
11) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659421 Disease Relevance 0.16 Pain Relevance 0
A single-nucleotide polymorphism in the glucocorticoid receptor gene in the region encoding the 3’UTR of hGR?
Gene_expression (encoding) of UTR
12) Confidence 0.06 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2716050 Disease Relevance 1.01 Pain Relevance 0.13
untranslated (UTR) region of ACCN1, and investigated the MS association of Single Nucleotide Polymorphisms (SNPs) identified in that region.
Gene_expression (region) of UTR
13) Confidence 0.05 Published 2007 Journal PLoS ONE Section Abstract Doc Link PMC1868958 Disease Relevance 0.13 Pain Relevance 0
UTR, the splice site SNP associated with TRIMCyp, and TRIMCyp expression.
Gene_expression (expression) of UTR
14) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2982814 Disease Relevance 0 Pain Relevance 0

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